The clearance of dead cells by efferocytosis

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The prompt and efficient clearance of unwanted and abnormal cells by phagocytes is termed efferocytosis and is crucial for organism development, maintenance of tissue homeostasis, and regulation of the immune system. Dying cells are recognized by phagocytes through pathways initiated via "find me" signals, recognition via "eat me" signals and down-modulation of regulatory "don't eat me" signals...

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ژورنال

عنوان ژورنال: Nature Reviews Molecular Cell Biology

سال: 2020

ISSN: 1471-0072,1471-0080

DOI: 10.1038/s41580-020-0232-1